PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
28629701-6	2017	RESULTS TREATMENT: with the PMF mixture elicited the suppression of melanogenesis, the degradation of tyrosinase in lysosomes and the mislocalization of tyrosinase associated with the acidification of intracellular organelles, including melanosomes.	Phenylmethylsulfonyl Fluoride	28-31	tyrosinase	Homo sapiens	102-112	
28629701-6	2017	RESULTS TREATMENT: with the PMF mixture elicited the suppression of melanogenesis, the degradation of tyrosinase in lysosomes and the mislocalization of tyrosinase associated with the acidification of intracellular organelles, including melanosomes.	Phenylmethylsulfonyl Fluoride	28-31	tyrosinase	Homo sapiens	153-163	
28629701-7	2017	The neutralization of cell organelle pH by ammonium chloride restored melanogenesis and the correct localization of tyrosinase to melanosomes, which had been suppressed by the PMF mixture.	Phenylmethylsulfonyl Fluoride	176-179	tyrosinase	Homo sapiens	116-126	
28629701-8	2017	CONCLUSION: These results suggest that the PMF mixture suppresses the localization of tyrosinase to melanosomes and consequently inhibits melanogenesis due to the acidification of cell organelles, including melanosomes.	Phenylmethylsulfonyl Fluoride	43-46	tyrosinase	Homo sapiens	86-96