PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
28531143-3	2017	In this study, we showed that a 4-phenoxyphenol derivative, 4-[4-(4-hydroxyphenoxy)phenoxy]phenol (4-HPPP), exerts an inhibitory activity against two HCC cell lines, Huh7 and Ha22T.	4-hppp	99-105	MIR7-3 host gene	Homo sapiens	166-170	
28531143-5	2017	Our results showed that higher dosage of 4-HPPP downregulates the expression of alpha-tubulin and causes nuclear enlargement in both the Huh-7 and Ha22T cell lines.	4-hppp	41-47	MIR7-3 host gene	Homo sapiens	137-142	
28531143-8	2017	The results of cellular proliferation assays, including trypan blue exclusion and colony formation, revealed that 4-HPPP inhibits the growth of Huh7 cells, but exerts less cytotoxicity in Ha22T cells.	4-hppp	114-120	MIR7-3 host gene	Homo sapiens	144-148	
28531143-10	2017	Western blotting results showed 4-HPPP caused the increase of pro-apoptotic factors including cleaved caspase-3, Bid and Bax in HCC cells, especially in Huh-7.	4-hppp	32-38	MIR7-3 host gene	Homo sapiens	153-158	
28531143-12	2017	Additionally, the level of gammaH2A histone family, member X (gammaH2AX), an endogenous DNA damage biomarker, was dramatically increased in Huh7 cells after 4-HPPP treatment, suggesting the involvement of DNA damage pathway in 4-HPPP-induced apoptosis.	4-hppp	157-163	MIR7-3 host gene	Homo sapiens	140-144	
28531143-12	2017	Additionally, the level of gammaH2A histone family, member X (gammaH2AX), an endogenous DNA damage biomarker, was dramatically increased in Huh7 cells after 4-HPPP treatment, suggesting the involvement of DNA damage pathway in 4-HPPP-induced apoptosis.	4-hppp	227-233	MIR7-3 host gene	Homo sapiens	140-144