PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
28528971-0	2017	Regulatory effects of 4-methoxychalcone on adipocyte differentiation through PPARgamma activation and reverse effect on TNF-alpha in 3T3-L1 cells.	4'-methoxychalcone	22-39	peroxisome proliferator activated receptor gamma	Mus musculus	77-86	
28528971-4	2017	Additionally, treatment with 4-MC significantly increased the PPARgamma-induced transcriptional activity and 4-MC also enhanced the DNA binding affinity of PPARgamma to the proliferator-activated receptor response elements (PPRE) at target promoters.	4'-methoxychalcone	29-33	peroxisome proliferator activated receptor gamma	Mus musculus	62-71	
28528971-4	2017	Additionally, treatment with 4-MC significantly increased the PPARgamma-induced transcriptional activity and 4-MC also enhanced the DNA binding affinity of PPARgamma to the proliferator-activated receptor response elements (PPRE) at target promoters.	4'-methoxychalcone	29-33	peroxisome proliferator activated receptor gamma	Mus musculus	156-165	
28528971-4	2017	Additionally, treatment with 4-MC significantly increased the PPARgamma-induced transcriptional activity and 4-MC also enhanced the DNA binding affinity of PPARgamma to the proliferator-activated receptor response elements (PPRE) at target promoters.	4'-methoxychalcone	109-113	peroxisome proliferator activated receptor gamma	Mus musculus	156-165	
28528971-6	2017	Treatment with 4-MC enhanced the lipid accumulation and strongly up-regulated the expression of adipogenic markers, including PPARgamma, aP2, FAS, and adiponectin during adipocyte differentiation.	4'-methoxychalcone	15-19	peroxisome proliferator activated receptor gamma	Mus musculus	126-135	
28528971-8	2017	This study clearly demonstrates that 4-MC enhanced adipocyte differentiation, in part, by its potent effects on PPARgamma activation and by its reverse effect on TNF-alpha.	4'-methoxychalcone	37-41	peroxisome proliferator activated receptor gamma	Mus musculus	112-121