PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 28502303-5 2017 The expressions of P21 and c-caspase-3 increased, meanwhile, the expressions of CDK4, cyclin D1, caspase-3 and Bcl-2 decreased by metformin. Metformin 130-139 KRAS proto-oncogene, GTPase Rattus norvegicus 19-22