PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 28473727-0 2017 Cryptolepine inhibits melanoma cell growth through coordinated changes in mitochondrial biogenesis, dynamics and metabolic tumor suppressor AMPKalpha1/2-LKB1. cryptolepine 0-12 protein kinase AMP-activated catalytic subunit alpha 1 Homo sapiens 140-150 28473727-0 2017 Cryptolepine inhibits melanoma cell growth through coordinated changes in mitochondrial biogenesis, dynamics and metabolic tumor suppressor AMPKalpha1/2-LKB1. cryptolepine 0-12 serine/threonine kinase 11 Homo sapiens 153-157 28473727-4 2017 The inhibitory effect of cryptolepine was associated with loss of mitochondrial membrane potential and reduced protein expression of Mfn1, Mfn2, Opa1 and p-Drp1 leading to disruption of mitochondrial dynamics. cryptolepine 25-37 mitofusin 1 Homo sapiens 133-137 28473727-4 2017 The inhibitory effect of cryptolepine was associated with loss of mitochondrial membrane potential and reduced protein expression of Mfn1, Mfn2, Opa1 and p-Drp1 leading to disruption of mitochondrial dynamics. cryptolepine 25-37 mitofusin 2 Homo sapiens 139-143 28473727-4 2017 The inhibitory effect of cryptolepine was associated with loss of mitochondrial membrane potential and reduced protein expression of Mfn1, Mfn2, Opa1 and p-Drp1 leading to disruption of mitochondrial dynamics. cryptolepine 25-37 OPA1 mitochondrial dynamin like GTPase Homo sapiens 145-149 28473727-6 2017 Decreased expression of SDH-A and COX-I demonstrated that cryptolepine treatment reduced mitochondrial biogenesis. cryptolepine 58-70 succinate dehydrogenase complex flavoprotein subunit A Homo sapiens 24-29