PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 28359840-5 2017 Similarly, in SAMHD1 knockout cells, HIV-1 showed increased replicative capacity in the presence of nucleoside inhibitors, especially AZT, that was reverted by re-expression of wild type SAMHD1. Nucleosides 100-110 SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1 Homo sapiens 14-20 28359840-5 2017 Similarly, in SAMHD1 knockout cells, HIV-1 showed increased replicative capacity in the presence of nucleoside inhibitors, especially AZT, that was reverted by re-expression of wild type SAMHD1. Nucleosides 100-110 SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1 Homo sapiens 187-193 28359840-8 2017 Our results demonstrate that SAMHD1 is active in HIV-1 permissive cells, does not modify susceptibility to HIV-1 infection but strongly affects sensitivity to nucleoside inhibitors. Nucleosides 159-169 SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1 Homo sapiens 29-35