PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
28334607-0	2017	The SARM1 Toll/Interleukin-1 Receptor Domain Possesses Intrinsic NAD+ Cleavage Activity that Promotes Pathological Axonal Degeneration.	NAD	65-69	sterile alpha and TIR motif containing 1	Homo sapiens	4-9	
28334607-2	2017	SARM1 is the central executioner of the axonal degeneration pathway that culminates in depletion of axonal NAD+, yet the identity of the underlying NAD+-depleting enzyme(s) is unknown.	NAD	107-111	sterile alpha and TIR motif containing 1	Homo sapiens	0-5	
28334607-2	2017	SARM1 is the central executioner of the axonal degeneration pathway that culminates in depletion of axonal NAD+, yet the identity of the underlying NAD+-depleting enzyme(s) is unknown.	NAD	148-152	sterile alpha and TIR motif containing 1	Homo sapiens	0-5	
28334607-3	2017	Here, in a series of experiments using purified proteins from mammalian cells, bacteria, and a cell-free protein translation system, we show that the SARM1-TIR domain itself has intrinsic NADase activity-cleaving NAD+ into ADP-ribose (ADPR), cyclic ADPR, and nicotinamide, with nicotinamide serving as a feedback inhibitor of the enzyme.	NAD	213-217	sterile alpha and TIR motif containing 1	Homo sapiens	150-155	
28334607-3	2017	Here, in a series of experiments using purified proteins from mammalian cells, bacteria, and a cell-free protein translation system, we show that the SARM1-TIR domain itself has intrinsic NADase activity-cleaving NAD+ into ADP-ribose (ADPR), cyclic ADPR, and nicotinamide, with nicotinamide serving as a feedback inhibitor of the enzyme.	Adenosine Diphosphate Ribose	223-233	sterile alpha and TIR motif containing 1	Homo sapiens	150-155	
28334607-3	2017	Here, in a series of experiments using purified proteins from mammalian cells, bacteria, and a cell-free protein translation system, we show that the SARM1-TIR domain itself has intrinsic NADase activity-cleaving NAD+ into ADP-ribose (ADPR), cyclic ADPR, and nicotinamide, with nicotinamide serving as a feedback inhibitor of the enzyme.	Cyclic ADP-Ribose	242-253	sterile alpha and TIR motif containing 1	Homo sapiens	150-155	
28334607-3	2017	Here, in a series of experiments using purified proteins from mammalian cells, bacteria, and a cell-free protein translation system, we show that the SARM1-TIR domain itself has intrinsic NADase activity-cleaving NAD+ into ADP-ribose (ADPR), cyclic ADPR, and nicotinamide, with nicotinamide serving as a feedback inhibitor of the enzyme.	Niacinamide	259-271	sterile alpha and TIR motif containing 1	Homo sapiens	150-155	
28334607-3	2017	Here, in a series of experiments using purified proteins from mammalian cells, bacteria, and a cell-free protein translation system, we show that the SARM1-TIR domain itself has intrinsic NADase activity-cleaving NAD+ into ADP-ribose (ADPR), cyclic ADPR, and nicotinamide, with nicotinamide serving as a feedback inhibitor of the enzyme.	Niacinamide	278-290	sterile alpha and TIR motif containing 1	Homo sapiens	150-155	
28334607-4	2017	Using traumatic and vincristine-induced injury models in neurons, we demonstrate that the NADase activity of full-length SARM1 is required in axons to promote axonal NAD+ depletion and axonal degeneration after injury.	Vincristine	20-31	sterile alpha and TIR motif containing 1	Homo sapiens	121-126	
28334607-4	2017	Using traumatic and vincristine-induced injury models in neurons, we demonstrate that the NADase activity of full-length SARM1 is required in axons to promote axonal NAD+ depletion and axonal degeneration after injury.	NAD	166-170	sterile alpha and TIR motif containing 1	Homo sapiens	121-126