PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 28324042-3 2017 Objectives: We hypothesized that in obesity IL-1 antagonism would result in downregulation of the hypothalamo-pituitary-adrenal axis, leading to decreased cortisol levels. Hydrocortisone 155-163 interleukin 1 beta Homo sapiens 44-48 28324042-8 2017 Median morning serum cortisol levels (nmol/L) decreased significantly after IL-1 antagonism [from baseline, 452 to 423; absolute difference, -38.7; 95% confidence interval (CI), -64 to -13.4; P = 0.0019]. Hydrocortisone 21-29 interleukin 1 beta Homo sapiens 76-80