PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 28226315-8 2018 Combined treatment with LEE011 and 5-fluorouracil or everolimus showed a significant enhancement in the inhibition of cell viability when compared to single-substance treatments due to PI3K-Akt-mTOR and Ras-Raf-MEK-ERK pathway downregulation and cooperative downregulation of cell cycle components. Fluorouracil 35-49 mitogen-activated protein kinase 1 Homo sapiens 215-218