PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
28199387-0	2017	Dermatan sulfate is a player in the transglutaminase 2 interaction network.	Dermatan Sulfate	0-16	transglutaminase 2	Homo sapiens	36-54	
28199387-3	2017	The enhanced extracellular expression of TG2 is associated with processes such as wound healing, fibrosis or vascular remodeling that are also characterized by a high deposition of dermatan sulfate (DS) proteoglycans in the ECM.	Dermatan Sulfate	181-197	transglutaminase 2	Homo sapiens	41-44	
28199387-3	2017	The enhanced extracellular expression of TG2 is associated with processes such as wound healing, fibrosis or vascular remodeling that are also characterized by a high deposition of dermatan sulfate (DS) proteoglycans in the ECM.	Dermatan Sulfate	199-201	transglutaminase 2	Homo sapiens	41-44	
28199387-4	2017	However, it is unknown whether DS may bind to TG2 or affect its function.	Dermatan Sulfate	31-33	transglutaminase 2	Homo sapiens	46-49	
28199387-5	2017	Using the plasmon surface resonance method, we showed that DS chains, especially those of biglycan, are good binding partners for TG2.	Dermatan Sulfate	59-61	transglutaminase 2	Homo sapiens	130-133	
28199387-7	2017	The competitive effect of heparin on DS binding to TG2 suggests that both glycosaminoglycans occupy the same binding site(s) on the protein molecule.	Dermatan Sulfate	37-39	transglutaminase 2	Homo sapiens	51-54	
28199387-8	2017	An occurrence of the DS-TG2 interaction was confirmed by the co-immunoprecipitation of this protein with native decorin that is a DS-bearing proteoglycan rather than with the decorin core protein.	Dermatan Sulfate	21-23	transglutaminase 2	Homo sapiens	24-27	
28199387-9	2017	Moreover, in vivo DS is responsible for both TG2 binding and the regulation of the location of this protein in the ECM as can be suggested from an increased extraction of TG2 from the human fascia only when an enzymatic degradation of the tissue DS was conducted in the presence of the anti-collagen type I antiserum.	Dermatan Sulfate	18-20	transglutaminase 2	Homo sapiens	45-48	
28199387-9	2017	Moreover, in vivo DS is responsible for both TG2 binding and the regulation of the location of this protein in the ECM as can be suggested from an increased extraction of TG2 from the human fascia only when an enzymatic degradation of the tissue DS was conducted in the presence of the anti-collagen type I antiserum.	Dermatan Sulfate	18-20	transglutaminase 2	Homo sapiens	171-174	
28199387-10	2017	In addition, DS with a low affinity for TG2 exerted an inhibitory effect on the protein transamidating activity most probably via the control of the accessibility of a substrate.	Dermatan Sulfate	13-15	transglutaminase 2	Homo sapiens	40-43	
28199387-11	2017	Our data show that DS can affect several aspects of TG2 biology in both physiological and pathological conditions.	Dermatan Sulfate	19-21	transglutaminase 2	Homo sapiens	52-55