PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 27881606-2 2017 Damaged mitochondria release danger molecules, such as reactive oxygen species, DNA, and cardiolipin, which can cause NLRP3 inflammasome activation and upregulation of IL-18 and IL-1beta It is not known if mitochondrial damage persists long after ischemia to sustain chronic inflammasome activation. Reactive Oxygen Species 55-78 NLR family, pyrin domain containing 3 Rattus norvegicus 118-123