PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 27855360-3 2017 This study shows that the 3-benzyloxy-beta-nitrostyrene analogues are potent inhibitors of the MAO-B isoform with IC50 values in the nanomolar range (39-565 nM). 3-benzyloxy-beta-nitrostyrene 26-55 monoamine oxidase B Homo sapiens 95-100 27855360-5 2017 Since some of the 3-benzyloxy-beta-nitrostyrene analogues possess potencies that are comparable to that of the reversible inhibitor, safinamide (IC50 = 0.080 muM), it may be concluded that this class may be promising leads for the development of reversible and selective MAO-B inhibitors, that may be useful for the management of Parkinson"s disease. 3-benzyloxy-beta-nitrostyrene 18-47 monoamine oxidase B Homo sapiens 271-276