PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 2783381-9 1989 We propose that ER+ breast cancer that has changed to a paracrine growth factor-driven system (from stromal cells or ER- breast cancer cells) is less responsive to gonadal steroids. Steroids 172-180 estrogen receptor 1 Homo sapiens 16-18