PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 27777210-8 2016 Both RITA and TMZ, especially the latter, significantly increased the expressions of p53, p21, puma, and other apoptosis-associated genes to accelerate apoptosis and inhibit the growth and colony formation of U87 cells, and the effect was more obvious with a combined treatment. Temozolomide 14-17 tumor protein p53 Homo sapiens 85-88