PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
27713966-0	2016	Hydroxysafflor yellow A inhibits IL-1beta-induced release of IL-6, IL-8, and MMP-1 via suppression of ERK, NF-kappaB and AP-1 signaling in SW982 human synovial cells.	hydroxysafflor yellow A	0-23	mitogen-activated protein kinase 1	Homo sapiens	102-105	
27713966-5	2016	HSYA also inhibited the phosphorylation of extracellular signal-regulated kinase (ERK), p65 and c-Jun.	hydroxysafflor yellow A	0-4	mitogen-activated protein kinase 1	Homo sapiens	43-80	
27713966-5	2016	HSYA also inhibited the phosphorylation of extracellular signal-regulated kinase (ERK), p65 and c-Jun.	hydroxysafflor yellow A	0-4	mitogen-activated protein kinase 1	Homo sapiens	82-85	
27713966-7	2016	These results indicate that the inhibitory effects of HSYA on IL-1beta-induced IL-6, IL-8 and MMP-1 release might be mediated via suppression of ERK, nuclear factor-kappaB (NF-kappaB) and activator protein-1 (AP-1) signaling pathways.	hydroxysafflor yellow A	54-58	mitogen-activated protein kinase 1	Homo sapiens	145-148