PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 27633058-0 2016 Silencing of CDC20 suppresses metastatic castration-resistant prostate cancer growth and enhances chemosensitivity to docetaxel. Docetaxel 118-127 cell division cycle 20 Mus musculus 13-18 27633058-1 2016 The role of cell division cycle 20 (CDC20) was investigated in chemoresistance to decetaxel and the underlying mechanisms in metastatic castration-resistant prostate cancer (mCRPC). decetaxel 82-91 cell division cycle 20 Mus musculus 36-41 27633058-2 2016 MTT assays were performed to determine effects of siRNA-mediated CDC20 knockdown on cell proliferation and anticancer activity of docetaxel. Docetaxel 130-139 cell division cycle 20 Mus musculus 65-70 27633058-6 2016 Knockdown of CDC20 suppressed cell proliferation and enhanced anticancer effect of docetaxel with IC50 reducing from 0.358 to 0.188 microg/ml in PC3 cells and 0.307 to 0.162 microg/ml in DU145 cells (P<0.01). Docetaxel 83-92 cell division cycle 20 Homo sapiens 13-18 27633058-10 2016 Silencing of CDC20 may be a new strategy to improve chemosensitization to docetaxel in mCRPC. Docetaxel 74-83 cell division cycle 20 Mus musculus 13-18