PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
27615060-0	2017	Evaluation of the rotenone-induced activation of the Nrf2 pathway in a neuronal model derived from human induced pluripotent stem cells.	Rotenone	18-26	NFE2 like bZIP transcription factor 2	Homo sapiens	53-57	
27615060-5	2017	Therefore, in the current study, we evaluated whether Nrf2 signaling machinery is expressed in human induced pluripotent stem cells (hiPSCs)-derived mixed neuronal/glial culture and if so whether it becomes activated by rotenone-induced oxidative stress mediated by complex I inhibition of mitochondrial respiration.	Rotenone	220-228	NFE2 like bZIP transcription factor 2	Homo sapiens	54-58	
27615060-6	2017	Rotenone was found to induce the activation of Nrf2 signaling particularly at the highest tested concentration (100 nM), as shown by Nrf2 nuclear translocation and the up-regulation of the Nrf2-downstream antioxidant enzymes, NQO1 and SRXN1.	Rotenone	0-8	NFE2 like bZIP transcription factor 2	Homo sapiens	47-51	
27615060-6	2017	Rotenone was found to induce the activation of Nrf2 signaling particularly at the highest tested concentration (100 nM), as shown by Nrf2 nuclear translocation and the up-regulation of the Nrf2-downstream antioxidant enzymes, NQO1 and SRXN1.	Rotenone	0-8	NFE2 like bZIP transcription factor 2	Homo sapiens	133-137	
27615060-6	2017	Rotenone was found to induce the activation of Nrf2 signaling particularly at the highest tested concentration (100 nM), as shown by Nrf2 nuclear translocation and the up-regulation of the Nrf2-downstream antioxidant enzymes, NQO1 and SRXN1.	Rotenone	0-8	NFE2 like bZIP transcription factor 2	Homo sapiens	133-137	
27615060-7	2017	Interestingly, exposure to rotenone also increased the number of astroglial cells in which Nrf2 activation may play an important role in neuroprotection.	Rotenone	27-35	NFE2 like bZIP transcription factor 2	Homo sapiens	91-95