PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
27551463-0	2015	SAG-UPS attenuates proapoptotic SARM and Noxa to confer survival advantage to early hepatocellular carcinoma.	sagopilone	0-3	sterile alpha and TIR motif containing 1	Homo sapiens	32-36	
27551463-0	2015	SAG-UPS attenuates proapoptotic SARM and Noxa to confer survival advantage to early hepatocellular carcinoma.	sagopilone	0-3	phorbol-12-myristate-13-acetate-induced protein 1	Homo sapiens	41-45	
27551463-6	2015	SAG-overexpressing HCC cell lines display reduced SARM and Noxa (but not Bcl-2, Bax and Bcl-xL), suggesting that SARM and Noxa are specific substrates of SAG-dependent ubiquitination.	sagopilone	0-3	sterile alpha and TIR motif containing 1	Homo sapiens	50-54	
27551463-6	2015	SAG-overexpressing HCC cell lines display reduced SARM and Noxa (but not Bcl-2, Bax and Bcl-xL), suggesting that SARM and Noxa are specific substrates of SAG-dependent ubiquitination.	sagopilone	0-3	phorbol-12-myristate-13-acetate-induced protein 1	Homo sapiens	59-63	
27551463-6	2015	SAG-overexpressing HCC cell lines display reduced SARM and Noxa (but not Bcl-2, Bax and Bcl-xL), suggesting that SARM and Noxa are specific substrates of SAG-dependent ubiquitination.	sagopilone	0-3	sterile alpha and TIR motif containing 1	Homo sapiens	113-117	
27551463-6	2015	SAG-overexpressing HCC cell lines display reduced SARM and Noxa (but not Bcl-2, Bax and Bcl-xL), suggesting that SARM and Noxa are specific substrates of SAG-dependent ubiquitination.	sagopilone	0-3	phorbol-12-myristate-13-acetate-induced protein 1	Homo sapiens	122-126	
27551463-6	2015	SAG-overexpressing HCC cell lines display reduced SARM and Noxa (but not Bcl-2, Bax and Bcl-xL), suggesting that SARM and Noxa are specific substrates of SAG-dependent ubiquitination.	sagopilone	154-157	sterile alpha and TIR motif containing 1	Homo sapiens	113-117	
27551463-6	2015	SAG-overexpressing HCC cell lines display reduced SARM and Noxa (but not Bcl-2, Bax and Bcl-xL), suggesting that SARM and Noxa are specific substrates of SAG-dependent ubiquitination.	sagopilone	154-157	phorbol-12-myristate-13-acetate-induced protein 1	Homo sapiens	122-126	
27551463-8	2015	SAG knockdown significantly elevated apoptosis with increased cytosolic cytochrome c, confirming SAG-mediated antiapoptosis in HCC.	sagopilone	0-3	cytochrome c, somatic	Homo sapiens	72-84	
27551463-9	2015	SAG overexpression stimulated protumorigenic cytokines, IL-1beta, IL-6 and TNF, but not antitumorigenic IL-12p40 and anti-inflammatory IL-10.	sagopilone	0-3	interleukin 1 beta	Homo sapiens	56-64	
27551463-9	2015	SAG overexpression stimulated protumorigenic cytokines, IL-1beta, IL-6 and TNF, but not antitumorigenic IL-12p40 and anti-inflammatory IL-10.	sagopilone	0-3	interleukin 6	Homo sapiens	66-70	
27551463-11	2015	Altogether, early stage-upregulated SAG-UPS exacerbates hepatocarcinogenesis progression, through: (1) ubiquitination-mediated degradation of proapoptotic SARM and Noxa; and (2) production of protumorigenic cytokines that induce a protumorigenic microenvironment, conferring survival advantage to HCC cells.	sagopilone	36-39	sterile alpha and TIR motif containing 1	Homo sapiens	155-159	
27551463-11	2015	Altogether, early stage-upregulated SAG-UPS exacerbates hepatocarcinogenesis progression, through: (1) ubiquitination-mediated degradation of proapoptotic SARM and Noxa; and (2) production of protumorigenic cytokines that induce a protumorigenic microenvironment, conferring survival advantage to HCC cells.	sagopilone	36-39	phorbol-12-myristate-13-acetate-induced protein 1	Homo sapiens	164-168