PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
27488947-0	2016	Metformin Enhances the Therapy Effects of Anti-IGF-1R mAb Figitumumab to NSCLC.	Metformin	0-9	insulin like growth factor 1 receptor	Homo sapiens	47-53	
27488947-7	2016	Metformin could target IGF-1R signaling pathway by attenuating PI3K/AKT and MEK/ERK signaling pathways and down-regulating IGF-1R.	Metformin	0-9	insulin like growth factor 1 receptor	Homo sapiens	23-29	
27488947-7	2016	Metformin could target IGF-1R signaling pathway by attenuating PI3K/AKT and MEK/ERK signaling pathways and down-regulating IGF-1R.	Metformin	0-9	insulin like growth factor 1 receptor	Homo sapiens	123-129	
27488947-8	2016	Finally, we found that combining metformin with CP could further induce IGF-1R down-regulation and was more effective to target NSCLC cells.	Metformin	33-42	insulin like growth factor 1 receptor	Homo sapiens	72-78