PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
27461790-0	2016	Blockade of Cannabinoid CB1 receptor attenuates the acquisition of morphine-induced conditioned place preference along with a downregulation of ERK, CREB phosphorylation, and BDNF expression in the nucleus accumbens and hippocampus.	Morphine	67-75	cannabinoid receptor 1 (brain)	Mus musculus	24-27	
27461790-7	2016	We found an increase of CB1R expression in the NAc and hippocampus of the mice following morphine CPP, but not those after repeated morphine in home cage without context exposure (NO-CPP).	Morphine	89-97	cannabinoid receptor 1 (brain)	Mus musculus	24-28	
27461790-10	2016	Collectively, these findings demonstrate that (1) Repeated morphine with context exposures but not merely the pharmacological effects of morphine increased CB1R expression both in the NAc and hippocampus.	Morphine	59-67	cannabinoid receptor 1 (brain)	Mus musculus	156-160	
27461790-11	2016	(2) CB1R antagonist mediated blockade of ERK-CREB-BDNF signaling activation in the NAc and hippocampus may be an important mechanism underlying the attenuation of morphine CPP.	Morphine	163-171	cannabinoid receptor 1 (brain)	Mus musculus	4-8