PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
27443158-0	2017	Duloxetine Reduces Oxidative Stress, Apoptosis, and Ca2+ Entry Through Modulation of TRPM2 and TRPV1 Channels in the Hippocampus and Dorsal Root Ganglion of Rats.	Duloxetine Hydrochloride	0-10	transient receptor potential cation channel, subfamily M, member 2	Rattus norvegicus	85-90	
27443158-3	2017	Duloxetine (DULOX) in neurons reduced the effects of Ca2+ entry and reactive oxygen species (ROS) through glutamate receptors, and this reduction of effects may also occur through TRPM2 and TRPV1 channels.	Duloxetine Hydrochloride	0-10	transient receptor potential cation channel, subfamily M, member 2	Rattus norvegicus	180-185	
27443158-7	2017	TRPM2 and TRPV1 channel current densities, [Ca2+] concentration, apoptosis, caspase 3, caspase 9, mitochondrial depolarization, and intracellular ROS production values in the neurons were lower in the DULOX group than in controls.	Duloxetine Hydrochloride	201-206	transient receptor potential cation channel, subfamily M, member 2	Rattus norvegicus	0-5	
27443158-9	2017	In conclusion, TRPM2 and TRPV1 channels are involved in Ca2+ entry-induced neuronal death and modulation of the activity of these channels by DULOX treatment may account for their neuroprotective activity against apoptosis, excessive ROS production, and Ca2+ entry.	Duloxetine Hydrochloride	142-147	transient receptor potential cation channel, subfamily M, member 2	Rattus norvegicus	15-20