PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 27391062-0 2016 Reactivation of ERK and Akt confers resistance of mutant BRAF colon cancer cells to the HSP90 inhibitor AUY922. 5-(2,4-dihydroxy-5-isopropylphenyl)-4-(4-morpholin-4-ylmethylphenyl)isoxazole-3-carboxylic acid ethylamide 104-110 mitogen-activated protein kinase 1 Homo sapiens 16-19 27391062-3 2016 Although AUY922 triggered rapid reduction in ERK and Akt activation in both wild-type and mutant BRAF colon cancer cells, activation of ERK and Akt rebounded shortly in the latter leading to resistance of the cells to AUY922-induced apoptosis. 5-(2,4-dihydroxy-5-isopropylphenyl)-4-(4-morpholin-4-ylmethylphenyl)isoxazole-3-carboxylic acid ethylamide 9-15 mitogen-activated protein kinase 1 Homo sapiens 45-48