PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
27294003-0	2016	Cisplatin suppresses the growth and proliferation of breast and cervical cancer cell lines by inhibiting integrin beta5-mediated glycolysis.	Cisplatin	0-9	integrin subunit beta 5	Homo sapiens	105-119	
27294003-5	2016	We demonstrated that cisplatin suppressed glycolysis-related proteins expression, including glucose transporter 1 (GLUT1), glucose transporter 4 (GLUT4) and lactate dehydrogenase B (LDHB), through down-regulating integrin beta5 (ITGB5)/focal adhesion kinase (FAK) signaling pathway.	Cisplatin	21-30	solute carrier family 2 member 1	Homo sapiens	92-113	
27294003-5	2016	We demonstrated that cisplatin suppressed glycolysis-related proteins expression, including glucose transporter 1 (GLUT1), glucose transporter 4 (GLUT4) and lactate dehydrogenase B (LDHB), through down-regulating integrin beta5 (ITGB5)/focal adhesion kinase (FAK) signaling pathway.	Cisplatin	21-30	solute carrier family 2 member 1	Homo sapiens	115-120	
27294003-5	2016	We demonstrated that cisplatin suppressed glycolysis-related proteins expression, including glucose transporter 1 (GLUT1), glucose transporter 4 (GLUT4) and lactate dehydrogenase B (LDHB), through down-regulating integrin beta5 (ITGB5)/focal adhesion kinase (FAK) signaling pathway.	Cisplatin	21-30	solute carrier family 2 member 4	Homo sapiens	123-144	
27294003-5	2016	We demonstrated that cisplatin suppressed glycolysis-related proteins expression, including glucose transporter 1 (GLUT1), glucose transporter 4 (GLUT4) and lactate dehydrogenase B (LDHB), through down-regulating integrin beta5 (ITGB5)/focal adhesion kinase (FAK) signaling pathway.	Cisplatin	21-30	solute carrier family 2 member 4	Homo sapiens	146-151	
27294003-5	2016	We demonstrated that cisplatin suppressed glycolysis-related proteins expression, including glucose transporter 1 (GLUT1), glucose transporter 4 (GLUT4) and lactate dehydrogenase B (LDHB), through down-regulating integrin beta5 (ITGB5)/focal adhesion kinase (FAK) signaling pathway.	Cisplatin	21-30	lactate dehydrogenase B	Homo sapiens	157-180	
27294003-5	2016	We demonstrated that cisplatin suppressed glycolysis-related proteins expression, including glucose transporter 1 (GLUT1), glucose transporter 4 (GLUT4) and lactate dehydrogenase B (LDHB), through down-regulating integrin beta5 (ITGB5)/focal adhesion kinase (FAK) signaling pathway.	Cisplatin	21-30	lactate dehydrogenase B	Homo sapiens	182-186	
27294003-5	2016	We demonstrated that cisplatin suppressed glycolysis-related proteins expression, including glucose transporter 1 (GLUT1), glucose transporter 4 (GLUT4) and lactate dehydrogenase B (LDHB), through down-regulating integrin beta5 (ITGB5)/focal adhesion kinase (FAK) signaling pathway.	Cisplatin	21-30	integrin subunit beta 5	Homo sapiens	213-227	
27294003-5	2016	We demonstrated that cisplatin suppressed glycolysis-related proteins expression, including glucose transporter 1 (GLUT1), glucose transporter 4 (GLUT4) and lactate dehydrogenase B (LDHB), through down-regulating integrin beta5 (ITGB5)/focal adhesion kinase (FAK) signaling pathway.	Cisplatin	21-30	integrin subunit beta 5	Homo sapiens	229-234	
27294003-5	2016	We demonstrated that cisplatin suppressed glycolysis-related proteins expression, including glucose transporter 1 (GLUT1), glucose transporter 4 (GLUT4) and lactate dehydrogenase B (LDHB), through down-regulating integrin beta5 (ITGB5)/focal adhesion kinase (FAK) signaling pathway.	Cisplatin	21-30	protein tyrosine kinase 2	Homo sapiens	259-262	
27294003-6	2016	ITGB5 overexpression rescued cisplatin-induced inhibition of cancer cell glycolysis, growth and proliferation.	Cisplatin	29-38	integrin subunit beta 5	Homo sapiens	0-5	
27294003-7	2016	Conclusively, we reveal a novel insight into cisplatin-induced anticancer mechanism, suggesting alternative strategies to the current therapeutic approaches of targeting ITGB5, as well as of a combination of cisplatin with glucose up-regulation chemotherapeutic agents to enhance anticancer effect.	Cisplatin	45-54	integrin subunit beta 5	Homo sapiens	170-175