PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
27200496-0	2017	Epigallocatechin gallate sensitizes cisplatin-resistant oral cancer CAR cell apoptosis and autophagy through stimulating AKT/STAT3 pathway and suppressing multidrug resistance 1 signaling.	epigallocatechin gallate	0-24	AKT serine/threonine kinase 1	Homo sapiens	121-124	
27200496-0	2017	Epigallocatechin gallate sensitizes cisplatin-resistant oral cancer CAR cell apoptosis and autophagy through stimulating AKT/STAT3 pathway and suppressing multidrug resistance 1 signaling.	epigallocatechin gallate	0-24	signal transducer and activator of transcription 3	Homo sapiens	125-130	
27200496-0	2017	Epigallocatechin gallate sensitizes cisplatin-resistant oral cancer CAR cell apoptosis and autophagy through stimulating AKT/STAT3 pathway and suppressing multidrug resistance 1 signaling.	epigallocatechin gallate	0-24	ATP binding cassette subfamily B member 1	Homo sapiens	155-177	
27200496-0	2017	Epigallocatechin gallate sensitizes cisplatin-resistant oral cancer CAR cell apoptosis and autophagy through stimulating AKT/STAT3 pathway and suppressing multidrug resistance 1 signaling.	Cisplatin	36-45	AKT serine/threonine kinase 1	Homo sapiens	121-124	
27200496-0	2017	Epigallocatechin gallate sensitizes cisplatin-resistant oral cancer CAR cell apoptosis and autophagy through stimulating AKT/STAT3 pathway and suppressing multidrug resistance 1 signaling.	Cisplatin	36-45	signal transducer and activator of transcription 3	Homo sapiens	125-130	
27200496-0	2017	Epigallocatechin gallate sensitizes cisplatin-resistant oral cancer CAR cell apoptosis and autophagy through stimulating AKT/STAT3 pathway and suppressing multidrug resistance 1 signaling.	Cisplatin	36-45	ATP binding cassette subfamily B member 1	Homo sapiens	155-177	
27200496-3	2017	EGCG inhibited cell viability in a time- and concentration-dependent manner by a sulforhodamine B (SRB) assay.	epigallocatechin gallate	0-4	chaperonin containing TCP1 subunit 4	Homo sapiens	81-97	
27200496-3	2017	EGCG inhibited cell viability in a time- and concentration-dependent manner by a sulforhodamine B (SRB) assay.	epigallocatechin gallate	0-4	chaperonin containing TCP1 subunit 4	Homo sapiens	99-102	
27200496-4	2017	EGCG induced CAR cell apoptosis and autophagy by 4",6-diamidino-2-phenylindole (DAPI) dye, acridine orange (AO) staining and green fluorescent protein (GFP)-tagged LC3B assay, respectively.	epigallocatechin gallate	0-4	microtubule associated protein 1 light chain 3 beta	Homo sapiens	164-168	
27200496-5	2017	EGCG also significantly enhanced caspase-9 and caspase-3 activities by caspase activity assay.	epigallocatechin gallate	0-4	caspase 9	Homo sapiens	33-42	
27200496-5	2017	EGCG also significantly enhanced caspase-9 and caspase-3 activities by caspase activity assay.	epigallocatechin gallate	0-4	caspase 3	Homo sapiens	47-56	
27200496-6	2017	EGCG markedly increased the protein levels of Bax, cleaved caspase-9, cleaved caspase-3, Atg5, Atg7, Atg12, Beclin-1, and LC3B-II, as well as significantly decreased the expression of Bcl-2, phosphorylated AKT (Ser473) and phosphorylation of STAT3 on Tyr705 by western blotting in CAR cells.	epigallocatechin gallate	0-4	BCL2 associated X, apoptosis regulator	Homo sapiens	46-49	
27200496-6	2017	EGCG markedly increased the protein levels of Bax, cleaved caspase-9, cleaved caspase-3, Atg5, Atg7, Atg12, Beclin-1, and LC3B-II, as well as significantly decreased the expression of Bcl-2, phosphorylated AKT (Ser473) and phosphorylation of STAT3 on Tyr705 by western blotting in CAR cells.	epigallocatechin gallate	0-4	caspase 9	Homo sapiens	59-68	
27200496-6	2017	EGCG markedly increased the protein levels of Bax, cleaved caspase-9, cleaved caspase-3, Atg5, Atg7, Atg12, Beclin-1, and LC3B-II, as well as significantly decreased the expression of Bcl-2, phosphorylated AKT (Ser473) and phosphorylation of STAT3 on Tyr705 by western blotting in CAR cells.	epigallocatechin gallate	0-4	caspase 3	Homo sapiens	78-87	
27200496-6	2017	EGCG markedly increased the protein levels of Bax, cleaved caspase-9, cleaved caspase-3, Atg5, Atg7, Atg12, Beclin-1, and LC3B-II, as well as significantly decreased the expression of Bcl-2, phosphorylated AKT (Ser473) and phosphorylation of STAT3 on Tyr705 by western blotting in CAR cells.	epigallocatechin gallate	0-4	autophagy related 5	Homo sapiens	89-93	
27200496-6	2017	EGCG markedly increased the protein levels of Bax, cleaved caspase-9, cleaved caspase-3, Atg5, Atg7, Atg12, Beclin-1, and LC3B-II, as well as significantly decreased the expression of Bcl-2, phosphorylated AKT (Ser473) and phosphorylation of STAT3 on Tyr705 by western blotting in CAR cells.	epigallocatechin gallate	0-4	autophagy related 7	Homo sapiens	95-99	
27200496-6	2017	EGCG markedly increased the protein levels of Bax, cleaved caspase-9, cleaved caspase-3, Atg5, Atg7, Atg12, Beclin-1, and LC3B-II, as well as significantly decreased the expression of Bcl-2, phosphorylated AKT (Ser473) and phosphorylation of STAT3 on Tyr705 by western blotting in CAR cells.	epigallocatechin gallate	0-4	autophagy related 12	Homo sapiens	101-106	
27200496-6	2017	EGCG markedly increased the protein levels of Bax, cleaved caspase-9, cleaved caspase-3, Atg5, Atg7, Atg12, Beclin-1, and LC3B-II, as well as significantly decreased the expression of Bcl-2, phosphorylated AKT (Ser473) and phosphorylation of STAT3 on Tyr705 by western blotting in CAR cells.	epigallocatechin gallate	0-4	beclin 1	Homo sapiens	108-116	
27200496-6	2017	EGCG markedly increased the protein levels of Bax, cleaved caspase-9, cleaved caspase-3, Atg5, Atg7, Atg12, Beclin-1, and LC3B-II, as well as significantly decreased the expression of Bcl-2, phosphorylated AKT (Ser473) and phosphorylation of STAT3 on Tyr705 by western blotting in CAR cells.	epigallocatechin gallate	0-4	microtubule associated protein 1 light chain 3 beta	Homo sapiens	122-126	
27200496-6	2017	EGCG markedly increased the protein levels of Bax, cleaved caspase-9, cleaved caspase-3, Atg5, Atg7, Atg12, Beclin-1, and LC3B-II, as well as significantly decreased the expression of Bcl-2, phosphorylated AKT (Ser473) and phosphorylation of STAT3 on Tyr705 by western blotting in CAR cells.	epigallocatechin gallate	0-4	BCL2 apoptosis regulator	Homo sapiens	184-189	
27200496-6	2017	EGCG markedly increased the protein levels of Bax, cleaved caspase-9, cleaved caspase-3, Atg5, Atg7, Atg12, Beclin-1, and LC3B-II, as well as significantly decreased the expression of Bcl-2, phosphorylated AKT (Ser473) and phosphorylation of STAT3 on Tyr705 by western blotting in CAR cells.	epigallocatechin gallate	0-4	AKT serine/threonine kinase 1	Homo sapiens	206-209	
27200496-6	2017	EGCG markedly increased the protein levels of Bax, cleaved caspase-9, cleaved caspase-3, Atg5, Atg7, Atg12, Beclin-1, and LC3B-II, as well as significantly decreased the expression of Bcl-2, phosphorylated AKT (Ser473) and phosphorylation of STAT3 on Tyr705 by western blotting in CAR cells.	epigallocatechin gallate	0-4	signal transducer and activator of transcription 3	Homo sapiens	242-247	
27200496-7	2017	Importantly, the protein and gene expression of multidrug resistance 1 (MDR1) were dose-dependently inhibited by EGCG.	epigallocatechin gallate	113-117	ATP binding cassette subfamily B member 1	Homo sapiens	48-70	
27200496-7	2017	Importantly, the protein and gene expression of multidrug resistance 1 (MDR1) were dose-dependently inhibited by EGCG.	epigallocatechin gallate	113-117	ATP binding cassette subfamily B member 1	Homo sapiens	72-76	
27200496-8	2017	Overall, downregulation of MDR1 levels and alterations of AKT/STAT3 signaling contributed to EGCG-induced apoptosis and autophagy in CAR cells.	epigallocatechin gallate	93-97	ATP binding cassette subfamily B member 1	Homo sapiens	27-31	
27200496-8	2017	Overall, downregulation of MDR1 levels and alterations of AKT/STAT3 signaling contributed to EGCG-induced apoptosis and autophagy in CAR cells.	epigallocatechin gallate	93-97	AKT serine/threonine kinase 1	Homo sapiens	58-61	
27200496-8	2017	Overall, downregulation of MDR1 levels and alterations of AKT/STAT3 signaling contributed to EGCG-induced apoptosis and autophagy in CAR cells.	epigallocatechin gallate	93-97	signal transducer and activator of transcription 3	Homo sapiens	62-67