PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 27194217-8 2016 At high concentrations (10-20 muM), PCB 52 induced more ROS than PCB 153 and PCB 180. Reactive Oxygen Species 56-59 pyruvate carboxylase Homo sapiens 36-39 27194217-9 2016 The role of extracellular signal-regulated kinase (ERK) 1/2 and/or ERK 5 signalling in PCB-induced ROS production was implicated through the reduction in ROS in the presence of the specific inhibitor U0126, whereas reduced ROS production after the use of SB203580 and SP600125 indicated the involvement of the p38 mitogen-activated protein kinase (MAPK) and c-Jun amino-terminal kinase (JNK) pathways, respectively. Reactive Oxygen Species 99-102 pyruvate carboxylase Homo sapiens 87-90 27194217-9 2016 The role of extracellular signal-regulated kinase (ERK) 1/2 and/or ERK 5 signalling in PCB-induced ROS production was implicated through the reduction in ROS in the presence of the specific inhibitor U0126, whereas reduced ROS production after the use of SB203580 and SP600125 indicated the involvement of the p38 mitogen-activated protein kinase (MAPK) and c-Jun amino-terminal kinase (JNK) pathways, respectively. Reactive Oxygen Species 154-157 pyruvate carboxylase Homo sapiens 87-90 27194217-9 2016 The role of extracellular signal-regulated kinase (ERK) 1/2 and/or ERK 5 signalling in PCB-induced ROS production was implicated through the reduction in ROS in the presence of the specific inhibitor U0126, whereas reduced ROS production after the use of SB203580 and SP600125 indicated the involvement of the p38 mitogen-activated protein kinase (MAPK) and c-Jun amino-terminal kinase (JNK) pathways, respectively. Reactive Oxygen Species 154-157 pyruvate carboxylase Homo sapiens 87-90 27194217-11 2016 The intracellular signalling mechanisms involved in ROS production in human neutrophil granulocytes appeared to be similar for PCB 52, PCB 153 and PCB 180. Reactive Oxygen Species 52-55 pyruvate carboxylase Homo sapiens 127-130 27194217-11 2016 The intracellular signalling mechanisms involved in ROS production in human neutrophil granulocytes appeared to be similar for PCB 52, PCB 153 and PCB 180. Reactive Oxygen Species 52-55 pyruvate carboxylase Homo sapiens 135-138 27194217-11 2016 The intracellular signalling mechanisms involved in ROS production in human neutrophil granulocytes appeared to be similar for PCB 52, PCB 153 and PCB 180. Reactive Oxygen Species 52-55 pyruvate carboxylase Homo sapiens 135-138