PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
27125949-3	2016	METHODS AND RESULTS: Mice deficient for oxygen sensor HIF-prolyl hydroxylase 1 (PHD1) were backcrossed onto an atherogenic low-density lipoprotein receptor (LDLR) knockout background and atherosclerosis was studied upon 8 weeks of western-type diet.	Oxygen	40-46	egl-9 family hypoxia-inducible factor 2	Mus musculus	54-78	
27125949-4	2016	PHD1-/-LDLR-/- mice presented a sharp reduction in VLDL and LDL plasma cholesterol levels.	Cholesterol	71-82	egl-9 family hypoxia-inducible factor 2	Mus musculus	0-4	
27125949-4	2016	PHD1-/-LDLR-/- mice presented a sharp reduction in VLDL and LDL plasma cholesterol levels.	Cholesterol	71-82	low density lipoprotein receptor	Mus musculus	7-11	
27125949-6	2016	Mechanistically, cholesterol-lowering in PHD1 deficient mice was a result of enhanced cholesterol excretion from blood to intestines and ultimately faeces.	Cholesterol	17-28	egl-9 family hypoxia-inducible factor 2	Mus musculus	41-45	
27125949-6	2016	Mechanistically, cholesterol-lowering in PHD1 deficient mice was a result of enhanced cholesterol excretion from blood to intestines and ultimately faeces.	Cholesterol	86-97	egl-9 family hypoxia-inducible factor 2	Mus musculus	41-45	
27125949-8	2016	In addition, when studying PHD1-/- in diet-induced obesity (14 weeks high-fat diet) mice were less glucose intolerant when compared with WT littermate controls.	Glucose	99-106	egl-9 family hypoxia-inducible factor 2	Mus musculus	27-31	
27125949-10	2016	Future studies should focus on the efficacy, safety, and gender-specific effects of PHD1 inhibition in humans, and unravel the molecular actors responsible for PHD1-driven, likely intestinal, and regulation of cholesterol metabolism.	Cholesterol	210-221	egl-9 family hypoxia inducible factor 2	Homo sapiens	160-164