PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 27106025-6 2016 Photoexcited nanocurcumin induced phosphorylation of c-Jun N-terminal kinase (JNK), mitochondrial depolarization, caspase-3 activation, and cleavage of poly (ADP-ribose) polymerase, indicating apoptotic cell death. nanocurcumin 13-25 mitogen-activated protein kinase 8 Homo sapiens 53-76 27106025-6 2016 Photoexcited nanocurcumin induced phosphorylation of c-Jun N-terminal kinase (JNK), mitochondrial depolarization, caspase-3 activation, and cleavage of poly (ADP-ribose) polymerase, indicating apoptotic cell death. nanocurcumin 13-25 mitogen-activated protein kinase 8 Homo sapiens 78-81 27106025-7 2016 Accordingly, pharmacologial inhibition of JNK and caspase activity rescued cancer cells from photoexcited nanocurcumin. nanocurcumin 106-118 mitogen-activated protein kinase 8 Homo sapiens 42-45 27106025-9 2016 By demonstrating the ability of photoexcited nanocurcumin to induce oxidative-stress independent, JNK- and caspase-dependent apoptosis, our results support its further investigation in cancer therapy. nanocurcumin 45-57 mitogen-activated protein kinase 8 Homo sapiens 98-114