PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 27078155-7 2016 Using cell-type selective markers, we observed that morphine reduced the number of late stage progenitors and immature neurons such as Doublecortin (DCX) and betaIII Tubulin (TuJ1) positive cells in the SGZ but did not reduce the number of early progenitors such as Nestin, SOX2, or neurogenic differentiation-1 (NeuroD1) positive cells. Morphine 52-60 doublecortin Mus musculus 149-152 27078155-7 2016 Using cell-type selective markers, we observed that morphine reduced the number of late stage progenitors and immature neurons such as Doublecortin (DCX) and betaIII Tubulin (TuJ1) positive cells in the SGZ but did not reduce the number of early progenitors such as Nestin, SOX2, or neurogenic differentiation-1 (NeuroD1) positive cells. Morphine 52-60 tubulin, beta 3 class III Mus musculus 158-173 27078155-7 2016 Using cell-type selective markers, we observed that morphine reduced the number of late stage progenitors and immature neurons such as Doublecortin (DCX) and betaIII Tubulin (TuJ1) positive cells in the SGZ but did not reduce the number of early progenitors such as Nestin, SOX2, or neurogenic differentiation-1 (NeuroD1) positive cells. Morphine 52-60 SRY (sex determining region Y)-box 2 Mus musculus 274-278 27078155-7 2016 Using cell-type selective markers, we observed that morphine reduced the number of late stage progenitors and immature neurons such as Doublecortin (DCX) and betaIII Tubulin (TuJ1) positive cells in the SGZ but did not reduce the number of early progenitors such as Nestin, SOX2, or neurogenic differentiation-1 (NeuroD1) positive cells. Morphine 52-60 neurogenic differentiation 1 Mus musculus 283-311 27078155-7 2016 Using cell-type selective markers, we observed that morphine reduced the number of late stage progenitors and immature neurons such as Doublecortin (DCX) and betaIII Tubulin (TuJ1) positive cells in the SGZ but did not reduce the number of early progenitors such as Nestin, SOX2, or neurogenic differentiation-1 (NeuroD1) positive cells. Morphine 52-60 neurogenic differentiation 1 Mus musculus 313-320 27078155-9 2016 In addition, when NeuroD1 was over-expressed in DG by stereotaxic injection of lentivirus, it rescued the loss of immature neurons and prolonged the extinction of morphine-trained CPP. Morphine 163-171 neurogenic differentiation 1 Mus musculus 18-25 27078155-10 2016 These results suggest that under the condition of CPP training paradigm, morphine affects the transition of neural progenitor/stem cells to immature neurons via a mechanism involving NeuroD1. Morphine 73-81 neurogenic differentiation 1 Mus musculus 183-190