PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 27059084-8 2016 We demonstrate that low oxygen stimulates a complex signaling network involving PI3K/Akt, Notch, and canonical Wnt pathways, which mediate the observed increase in nuclear Oct4a and REST, with simultaneous decrease in p53, AIF, and Bak. Oxygen 24-30 tumor protein p53 Homo sapiens 218-221