PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 27035420-3 2016 In the present study, it was observed that its genotoxic metabolite, anti-benzopyrene-7,8-diol-9,10-epoxide (BPDE), triggered cell cycle arrest in S-phase in 16HBE cells by activating ataxia-telangiectasia (ATM)/checkpoint kinase (Chk)2 and ATM and Rad3 related (ATR)/Chk1 signaling pathways. 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 109-113 checkpoint kinase 1 Homo sapiens 268-272