PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 2695506-7 1989 In the presence of LHRH-A, the stimulatory effect of arachidonic acid was additive up to a concentration of 100 microM; but higher concentrations of arachidonic acid (200 microM) were inhibitory. Arachidonic Acid 53-69 gonadotropin releasing hormone 1 Rattus norvegicus 19-23 2695506-7 1989 In the presence of LHRH-A, the stimulatory effect of arachidonic acid was additive up to a concentration of 100 microM; but higher concentrations of arachidonic acid (200 microM) were inhibitory. Arachidonic Acid 149-165 gonadotropin releasing hormone 1 Rattus norvegicus 19-23 2695506-8 1989 LHRH-A-induced steroidogenesis was inhibited by 5, 8, 11, 14 Eicosatetraynoic acid (ETYA), an inhibitor of all the three known pathways of arachidonic acid metabolism, and by nordihydroguaiaretic acid, and inhibitory of the lipoxygenase pathway of arachidonic acid metabolism. Arachidonic Acid 139-155 gonadotropin releasing hormone 1 Rattus norvegicus 0-4 2695506-8 1989 LHRH-A-induced steroidogenesis was inhibited by 5, 8, 11, 14 Eicosatetraynoic acid (ETYA), an inhibitor of all the three known pathways of arachidonic acid metabolism, and by nordihydroguaiaretic acid, and inhibitory of the lipoxygenase pathway of arachidonic acid metabolism. Arachidonic Acid 248-264 gonadotropin releasing hormone 1 Rattus norvegicus 0-4 2695506-12 1989 These results suggest that arachidonic acid, whose release is influenced by phospholipase C, is involved in LHRH-A-induced T secretion by rat Leydig cells. Arachidonic Acid 27-43 gonadotropin releasing hormone 1 Rattus norvegicus 108-112