PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 26918322-1 2016 Cytochrome P450 CYP26 enzymes are responsible for all-trans-retinoic acid (atRA) clearance. Tretinoin 50-73 cytochrome P450 family 26 subfamily A member 1 Homo sapiens 16-21 26918322-1 2016 Cytochrome P450 CYP26 enzymes are responsible for all-trans-retinoic acid (atRA) clearance. Tretinoin 75-79 cytochrome P450 family 26 subfamily A member 1 Homo sapiens 16-21 26918322-2 2016 Inhibition of CYP26 enzymes will increase endogenous atRA concentrations and is an attractive therapeutic target. Tretinoin 53-57 cytochrome P450 family 26 subfamily A member 1 Homo sapiens 14-19 26918322-3 2016 However, the selectivity and potency of the existing atRA metabolism inhibitors toward CYP26A1 and CYP26B1 is unknown, and no selective CYP26A1 or CYP26B1 inhibitors have been developed. Tretinoin 53-57 cytochrome P450 family 26 subfamily A member 1 Homo sapiens 87-94