PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 26884647-5 2016 RESULTS: We found that nicotine reduced the levels of M1 state markers, including inducible nitric oxide synthase (iNOS) expression and tumor necrosis factor alpha (TNF-alpha) and interleukin- (IL-) 6 releases; meanwhile, it increased the levels of M2 state markers, including arginase-1 (Arg-1) expression and brain-derived neurotrophic factor (BDNF) release, in the Abeta-stimulated microglia. Nicotine 23-31 tumor necrosis factor Homo sapiens 136-163 26884647-5 2016 RESULTS: We found that nicotine reduced the levels of M1 state markers, including inducible nitric oxide synthase (iNOS) expression and tumor necrosis factor alpha (TNF-alpha) and interleukin- (IL-) 6 releases; meanwhile, it increased the levels of M2 state markers, including arginase-1 (Arg-1) expression and brain-derived neurotrophic factor (BDNF) release, in the Abeta-stimulated microglia. Nicotine 23-31 tumor necrosis factor Homo sapiens 165-174