PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 26881175-7 2016 Nicotine also inhibited toxin A-induced increased colonic concentrations of the TRPV1 (transient receptor potential vanilloid subtype 1) agonist, leukotriene B4 (LTB4), and release of the proinflammatory neuropeptide, substance P. Pretreatment with nicotine did not protect against direct TRPV1-mediated colitis caused by intraluminal capsaicin. Nicotine 0-8 transient receptor potential cation channel, subfamily V, member 1 Rattus norvegicus 80-85 26881175-7 2016 Nicotine also inhibited toxin A-induced increased colonic concentrations of the TRPV1 (transient receptor potential vanilloid subtype 1) agonist, leukotriene B4 (LTB4), and release of the proinflammatory neuropeptide, substance P. Pretreatment with nicotine did not protect against direct TRPV1-mediated colitis caused by intraluminal capsaicin. Nicotine 0-8 transient receptor potential cation channel, subfamily V, member 1 Rattus norvegicus 87-135 26881175-7 2016 Nicotine also inhibited toxin A-induced increased colonic concentrations of the TRPV1 (transient receptor potential vanilloid subtype 1) agonist, leukotriene B4 (LTB4), and release of the proinflammatory neuropeptide, substance P. Pretreatment with nicotine did not protect against direct TRPV1-mediated colitis caused by intraluminal capsaicin. Nicotine 0-8 transient receptor potential cation channel, subfamily V, member 1 Rattus norvegicus 289-294 26881175-8 2016 Nicotinic cholinergic receptors tonically protect the colon against inflammation and nicotine inhibits toxin A colitis but not toxin A ileitis in rats in part by inhibition of toxin A-induced activation of TRPV1 by endogenous TRPV1 agonists such as LTB4. Nicotine 85-93 transient receptor potential cation channel, subfamily V, member 1 Rattus norvegicus 206-211