PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 26722502-3 2015 In the present work, we studied the regulative effect of caveolin-1 on the expression of tight junction-associated proteins and BTB via directly silencing and overexpressing of caveolin-1 by recombinant adenovirus transduction of glioma-derived microvascular endothelial cells in rat brain. btb 128-131 caveolin 1 Rattus norvegicus 57-67 26722502-4 2015 The results show that the caveolin-1 downregulation resulted in decreased expression of tight junction-associated proteins, opening of tight junctions, and increasing the permeability of BTB, whereas the overexpression of caveolin-1 presented the opposite effects. btb 187-190 caveolin 1 Rattus norvegicus 26-36 26722502-5 2015 Therefore, we conclude that caveolin-1 regulates the expression of tight junction-associated proteins in a positive manner, which further plays a role in the regulation of BTB permeability. btb 172-175 caveolin 1 Rattus norvegicus 28-38