PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 26697130-4 2016 MCF-7 cells were treated with different concentrations of TAM and/or CAPE for 48 h. This novel combination exerted synergistic cytotoxic effects against MCF-7 cells via induction of apoptotic machinery with activation of caspases and DNA fragmentation, along with downregulation of Bcl-2 and Beclin 1 expression levels. caffeic acid phenethyl ester 69-73 BCL2 apoptosis regulator Homo sapiens 282-287