PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 26693911-0 2016 Dexamethasone Inhibits TGF-beta1-Induced Cell Migration by Regulating the ERK and AKT Pathways in Human Colon Cancer Cells Via CYR61. Dexamethasone 0-13 AKT serine/threonine kinase 1 Homo sapiens 82-85 26693911-7 2016 Alternatively, both migratory pathways, expression of AKT and ERK, and the target factor CYR61 was also tested by co-treatment with TGF-beta1 and dexamethasone. Dexamethasone 146-159 AKT serine/threonine kinase 1 Homo sapiens 54-57 26693911-10 2016 ERK and AKT signaling pathways were found to mediate TGF-beta1-induced migration, which was inhibited by dexamethasone. Dexamethasone 105-118 AKT serine/threonine kinase 1 Homo sapiens 8-11 26693911-14 2016 CONCLUSION: These findings suggested that dexamethasone inhibits AKT and ERK phosphorylation, leading to decreased CYR61 expression, which in turn blocks TGF-beta1-induced migration. Dexamethasone 42-55 AKT serine/threonine kinase 1 Homo sapiens 65-68