PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 26683992-0 2016 2-Chloro-4-[[(1R,2R)-2-hydroxy-2-methyl-cyclopentyl]amino]-3-methyl-benzonitrile: A Transdermal Selective Androgen Receptor Modulator (SARM) for Muscle Atrophy. CHEMBL3764185 0-80 sterile alpha and TIR motif containing 1 Homo sapiens 135-139 26683992-1 2016 A transdermal SARM has a potential to have therapeutic benefit through anabolic activity in muscle while sparing undesired effects of benign prostate hyperplasia (BPH) and liver-mediated decrease in HDL-C. 2-Chloro-4-[(2-hydroxy-2-methyl-cyclopentyl)amino]-3-methyl-benzonitrile 6 showed the desired muscle and prostate effects in a preclinical ORX rat model. 2-chloro-4-((2-hydroxy-2-methylcyclopentyl)amino)-3-methylbenzonitrile 206-278 sterile alpha and TIR motif containing 1 Homo sapiens 14-18