PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
26657295-0	2016	Metronomic topotecan impedes tumor growth of MYCN-amplified neuroblastoma cells in vitro and in vivo by therapy induced senescence.	Topotecan	11-20	MYCN proto-oncogene, bHLH transcription factor	Homo sapiens	45-49	
26657295-8	2016	Importantly, TPT-treated senescent tumor cells act growth-inhibitory in a dose-dependent manner on non-senescent tumor cells and MYCN expression is significantly reduced in vitro and in vivo.	Topotecan	13-16	MYCN proto-oncogene, bHLH transcription factor	Homo sapiens	129-133