PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
26646023-7	2016	RESULTS: Bupivacaine cardiotoxicity rapidly dephosphorylated Akt at S473 to 63 +- 5% of baseline and phosphorylated AMPK to 151 +- 19%.	Bupivacaine	9-20	AKT serine/threonine kinase 1	Homo sapiens	61-64	
26646023-11	2016	Irreversible inhibition of Pi3k upstream of Akt exacerbated bupivacaine cardiotoxicity, whereas pretreating with a reversible inhibitor delayed the onset of toxicity.	Bupivacaine	60-71	AKT serine/threonine kinase 1	Homo sapiens	44-47	
26646023-13	2016	CONCLUSION: Glucose handling by Akt and AMPK is integral to recovery from bupivacaine cardiotoxicity and modulation of these pathways by ILE contributes to lipid resuscitation.	Bupivacaine	74-85	AKT serine/threonine kinase 1	Homo sapiens	32-35