PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
26560363-0	2015	Regulation of iron homeostasis by the p53-ISCU pathway.	Iron	14-18	iron-sulfur cluster assembly enzyme	Homo sapiens	42-46	
26560363-2	2015	Here, we report that p53 regulates iron metabolism through the transcriptional regulation of ISCU (iron-sulfur cluster assembly enzyme), which encodes a scaffold protein that plays a critical role in Fe-S cluster biogenesis.	Iron	35-39	iron-sulfur cluster assembly enzyme	Homo sapiens	93-97	
26560363-2	2015	Here, we report that p53 regulates iron metabolism through the transcriptional regulation of ISCU (iron-sulfur cluster assembly enzyme), which encodes a scaffold protein that plays a critical role in Fe-S cluster biogenesis.	Iron	99-103	iron-sulfur cluster assembly enzyme	Homo sapiens	93-97	
26560363-2	2015	Here, we report that p53 regulates iron metabolism through the transcriptional regulation of ISCU (iron-sulfur cluster assembly enzyme), which encodes a scaffold protein that plays a critical role in Fe-S cluster biogenesis.	Iron	200-202	iron-sulfur cluster assembly enzyme	Homo sapiens	93-97	
26560363-4	2015	Knockdown of ISCU enhanced the binding of iron regulatory protein 1 (IRP1), a cytosolic Fe-S protein, to an iron-responsive element in the 5" UTR of ferritin heavy polypeptide 1 (FTH1) mRNA and subsequently reduced the translation of FTH1, a major iron storage protein.	Iron	42-46	iron-sulfur cluster assembly enzyme	Homo sapiens	13-17	
26560363-4	2015	Knockdown of ISCU enhanced the binding of iron regulatory protein 1 (IRP1), a cytosolic Fe-S protein, to an iron-responsive element in the 5" UTR of ferritin heavy polypeptide 1 (FTH1) mRNA and subsequently reduced the translation of FTH1, a major iron storage protein.	Iron	108-112	iron-sulfur cluster assembly enzyme	Homo sapiens	13-17	
26560363-9	2015	Our finding revealed a novel role of the p53-ISCU pathway in the maintenance of iron homeostasis in hepatocellular carcinogenesis.	Iron	80-84	iron-sulfur cluster assembly enzyme	Homo sapiens	45-49