PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
26494532-5	2015	The SMD simulations showed that the active pyridinium ring of K048 is directed towards the phosphorus atom conjugated to the active serine (SUN203) of tabun-mAChE(wild-type).	pyridine	43-53	acetylcholinesterase	Mus musculus	157-162	
26494532-7	2015	However, in the case of tabun-mutant mAChE(Y337A).K048 conjugate, the replacement of aromatic Tyr337 with the aliphatic alanine unit in the choline binding site, however, loses one of the pi-pi interaction between the active pyridinium ring of K048 and the Tyr337.	pyridine	225-235	acetylcholinesterase	Mus musculus	37-42	
26494532-10	2015	Furthermore, the unbinding of the K048 with SMD studies showed that the active pyridinium ring of the drug undergoes a complete turn along the gorge axis and is directed away from the phosphorus atom conjugated to the active serine of the tabun-mutant mAChE(Y337A).	pyridine	79-89	acetylcholinesterase	Mus musculus	252-257