PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 26482881-0 2015 NRF2 regulates serine biosynthesis in non-small cell lung cancer. Serine 15-21 NFE2 like bZIP transcription factor 2 Homo sapiens 0-4 26482881-4 2015 We found that NRF2 controls the expression of the key serine/glycine biosynthesis enzyme genes PHGDH, PSAT1 and SHMT2 via ATF4 to support glutathione and nucleotide production. Serine 54-60 NFE2 like bZIP transcription factor 2 Homo sapiens 14-18 26482881-4 2015 We found that NRF2 controls the expression of the key serine/glycine biosynthesis enzyme genes PHGDH, PSAT1 and SHMT2 via ATF4 to support glutathione and nucleotide production. Serine 54-60 phosphoglycerate dehydrogenase Homo sapiens 95-100 26482881-4 2015 We found that NRF2 controls the expression of the key serine/glycine biosynthesis enzyme genes PHGDH, PSAT1 and SHMT2 via ATF4 to support glutathione and nucleotide production. Serine 54-60 phosphoserine aminotransferase 1 Homo sapiens 102-107 26482881-4 2015 We found that NRF2 controls the expression of the key serine/glycine biosynthesis enzyme genes PHGDH, PSAT1 and SHMT2 via ATF4 to support glutathione and nucleotide production. Serine 54-60 serine hydroxymethyltransferase 2 Homo sapiens 112-117 26482881-4 2015 We found that NRF2 controls the expression of the key serine/glycine biosynthesis enzyme genes PHGDH, PSAT1 and SHMT2 via ATF4 to support glutathione and nucleotide production. Serine 54-60 activating transcription factor 4 Homo sapiens 122-126 26482881-4 2015 We found that NRF2 controls the expression of the key serine/glycine biosynthesis enzyme genes PHGDH, PSAT1 and SHMT2 via ATF4 to support glutathione and nucleotide production. Glycine 61-68 NFE2 like bZIP transcription factor 2 Homo sapiens 14-18 26482881-4 2015 We found that NRF2 controls the expression of the key serine/glycine biosynthesis enzyme genes PHGDH, PSAT1 and SHMT2 via ATF4 to support glutathione and nucleotide production. Glycine 61-68 phosphoglycerate dehydrogenase Homo sapiens 95-100 26482881-4 2015 We found that NRF2 controls the expression of the key serine/glycine biosynthesis enzyme genes PHGDH, PSAT1 and SHMT2 via ATF4 to support glutathione and nucleotide production. Glycine 61-68 phosphoserine aminotransferase 1 Homo sapiens 102-107 26482881-4 2015 We found that NRF2 controls the expression of the key serine/glycine biosynthesis enzyme genes PHGDH, PSAT1 and SHMT2 via ATF4 to support glutathione and nucleotide production. Glycine 61-68 serine hydroxymethyltransferase 2 Homo sapiens 112-117 26482881-4 2015 We found that NRF2 controls the expression of the key serine/glycine biosynthesis enzyme genes PHGDH, PSAT1 and SHMT2 via ATF4 to support glutathione and nucleotide production. Glycine 61-68 activating transcription factor 4 Homo sapiens 122-126 26482881-4 2015 We found that NRF2 controls the expression of the key serine/glycine biosynthesis enzyme genes PHGDH, PSAT1 and SHMT2 via ATF4 to support glutathione and nucleotide production. Glutathione 138-149 NFE2 like bZIP transcription factor 2 Homo sapiens 14-18 26482881-4 2015 We found that NRF2 controls the expression of the key serine/glycine biosynthesis enzyme genes PHGDH, PSAT1 and SHMT2 via ATF4 to support glutathione and nucleotide production. Glutathione 138-149 phosphoglycerate dehydrogenase Homo sapiens 95-100 26482881-4 2015 We found that NRF2 controls the expression of the key serine/glycine biosynthesis enzyme genes PHGDH, PSAT1 and SHMT2 via ATF4 to support glutathione and nucleotide production. Glutathione 138-149 phosphoserine aminotransferase 1 Homo sapiens 102-107 26482881-4 2015 We found that NRF2 controls the expression of the key serine/glycine biosynthesis enzyme genes PHGDH, PSAT1 and SHMT2 via ATF4 to support glutathione and nucleotide production. Glutathione 138-149 serine hydroxymethyltransferase 2 Homo sapiens 112-117 26482881-4 2015 We found that NRF2 controls the expression of the key serine/glycine biosynthesis enzyme genes PHGDH, PSAT1 and SHMT2 via ATF4 to support glutathione and nucleotide production. Glutathione 138-149 activating transcription factor 4 Homo sapiens 122-126 26482881-6 2015 Thus, a substantial fraction of human NSCLCs activates an NRF2-dependent transcriptional program that regulates serine and glycine metabolism and is linked to clinical aggressiveness. Serine 112-118 NFE2 like bZIP transcription factor 2 Homo sapiens 58-62 26482881-6 2015 Thus, a substantial fraction of human NSCLCs activates an NRF2-dependent transcriptional program that regulates serine and glycine metabolism and is linked to clinical aggressiveness. Glycine 123-130 NFE2 like bZIP transcription factor 2 Homo sapiens 58-62