PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
26421381-0	2016	Spectroscopic and MD simulation studies on unfolding processes of mitochondrial carbonic anhydrase VA induced by urea.	Urea	113-117	carbonic anhydrase 5A	Homo sapiens	80-101	
26421381-2	2016	To understand the biophysical properties of CAVA, we carried out a reversible urea-induced isothermal denaturation at pH 7.0 and 25 C. Spectroscopic probes, [theta]222 (mean residue ellipticity at 222 nm), F344 (Trp-fluorescence emission intensity at 344 nm) and Deltaepsilon280 (difference absorption at 280 nm) were used to monitor the effect of urea on the structure and stability of CAVA.	Urea	78-82	carbonic anhydrase 5A	Homo sapiens	44-48	
26421381-5	2016	We further performed 40 ns molecular dynamics simulation of CAVA to see the dynamics at different urea concentrations.	Urea	98-102	carbonic anhydrase 5A	Homo sapiens	60-64