PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 26397133-1 2015 In tobacco-associated lung cancers, the protein kinase B/mammalian target of rapamycin (Akt/mTOR) pathway frequently is activated by nicotine and its metabolite 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK). Nicotine 133-141 AKT serine/threonine kinase 1 Homo sapiens 88-91