PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
26374173-1	2015	Montelukast has been recommended as a selective in vitro and in vivo probe of cytochrome P450 (P450) CYP2C8 activity, but its selectivity toward this enzyme remains unclear.	montelukast	0-11	cytochrome P450 family 2 subfamily C member 8	Homo sapiens	101-107	
26374173-3	2015	Kinetic and inhibition experiments performed at therapeutically relevant concentrations reveal that CYP2C8 and CYP2C9 are the principal enzymes responsible for montelukast 36-hydroxylation to 1,2-diol.	montelukast	160-171	cytochrome P450 family 2 subfamily C member 8	Homo sapiens	100-106	
26374173-10	2015	The utility of montelukast as a probe of CYP2C8 activity may be compromised owing to involvement of multiple P450s and UGT1A3 in its metabolism.	montelukast	15-26	cytochrome P450 family 2 subfamily C member 8	Homo sapiens	41-47