PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 26322330-11 2015 Taken together, these data provide a mechanism by which phasic ACh release enhances the firing of a subset of hypocretin neurons through postsynaptic nAChRs, but disrupts tonic, presynaptic nAChR-mediated glutamatergic inputs to the overall population of hypocretin neurons, potentially enhancing the signal-to-noise ratio during the response of the nAChR-positive subset of neurons. Acetylcholine 63-66 cholinergic receptor, nicotinic, alpha polypeptide 7 Mus musculus 150-155 26322330-11 2015 Taken together, these data provide a mechanism by which phasic ACh release enhances the firing of a subset of hypocretin neurons through postsynaptic nAChRs, but disrupts tonic, presynaptic nAChR-mediated glutamatergic inputs to the overall population of hypocretin neurons, potentially enhancing the signal-to-noise ratio during the response of the nAChR-positive subset of neurons. Acetylcholine 63-66 cholinergic receptor, nicotinic, alpha polypeptide 7 Mus musculus 190-195