PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
26225832-0	2015	Cooperativity in CYP2E1 metabolism of acetaminophen and styrene mixtures.	Acetaminophen	38-51	cytochrome P450 family 2 subfamily E member 1	Homo sapiens	17-23	
26225832-2	2015	Herein, we demonstrated that in vitro CYP2E1 metabolic activation of acetaminophen and styrene mixtures could not be explained through the Michaelis-Menten mechanism or any models relying on that premise.	Acetaminophen	69-82	cytochrome P450 family 2 subfamily E member 1	Homo sapiens	38-44	
26225832-7	2015	In this case, acetaminophen competed with styrene for CYP2E1 (Ki=830muM and Ksi=180muM for catalytic and effector sites, respectively) and resulted in cooperative impacts on binding and catalysis.	Acetaminophen	14-27	cytochrome P450 family 2 subfamily E member 1	Homo sapiens	54-60