PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 26165503-9 2015 THE RESULTS: Dex increased intracellular ROS level, the expression of Akt, FOXO3 as well as autophagy flux in human chondrocytes. Dexamethasone 13-16 AKT serine/threonine kinase 1 Homo sapiens 70-73 26165503-11 2015 Catalase, the ROS scavenger, suppressed Dex-induced up-regulation of autophagy flux and expression of aggrecanases and Akt. Dexamethasone 40-43 AKT serine/threonine kinase 1 Homo sapiens 119-122 26165503-12 2015 MK-2206 and LY294002, the PI3K/Akt inhibitors, repressed Dex-induced up-regulation of FOXO3. Dexamethasone 57-60 AKT serine/threonine kinase 1 Homo sapiens 31-34 26165503-17 2015 Autophagy was induced in response to Dex-induced up-regulation of ROS via ROS/Akt/FOXO3 signal pathway. Dexamethasone 37-40 AKT serine/threonine kinase 1 Homo sapiens 78-81