PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 26121139-0 2015 Channel Activity of Cardiac Ryanodine Receptors (RyR2) Determines Potency and Efficacy of Flecainide and R-Propafenone against Arrhythmogenic Calcium Waves in Ventricular Cardiomyocytes. Propafenone 105-118 ryanodine receptor 2, cardiac Mus musculus 49-53 26121139-2 2015 We hypothesized that differences in RyR2 activity induced by CPVT mutations determines the potency of open-state RyR2 blockers like flecainide (FLEC) and R-propafenone (RPROP) against Ca2+ waves in cardiomyocytes. Propafenone 154-167 ryanodine receptor 2, cardiac Mus musculus 36-40 26121139-2 2015 We hypothesized that differences in RyR2 activity induced by CPVT mutations determines the potency of open-state RyR2 blockers like flecainide (FLEC) and R-propafenone (RPROP) against Ca2+ waves in cardiomyocytes. Propafenone 154-167 ryanodine receptor 2, cardiac Mus musculus 113-117 26121139-2 2015 We hypothesized that differences in RyR2 activity induced by CPVT mutations determines the potency of open-state RyR2 blockers like flecainide (FLEC) and R-propafenone (RPROP) against Ca2+ waves in cardiomyocytes. Propafenone 169-174 ryanodine receptor 2, cardiac Mus musculus 36-40 26121139-2 2015 We hypothesized that differences in RyR2 activity induced by CPVT mutations determines the potency of open-state RyR2 blockers like flecainide (FLEC) and R-propafenone (RPROP) against Ca2+ waves in cardiomyocytes. Propafenone 169-174 ryanodine receptor 2, cardiac Mus musculus 113-117